The South African-born de Lange’s best bowling figures were 5/60 which he attained against Zimbabwe in Edinburgh in June 2017.
After Scotland's historic first ODI win against a Full Member team, de Lange played five matches after that, before being sidelined for health reasons.
In October last year, the news of his illness was made public by his family as they launched a campaign to raise money for Charity. At the time, Malcolm Cannon, Cricket Scotland CEO, said, "Con has been a superb servant to the game of cricket in Scotland and is a very popular member of the squad.
"We are now delighted to help the cause by spreading the word throughout the broader cricketing family both at home and overseas and we know there will be an overwhelming level of support from this close-knit community.”
Cricket fraternity took to Twitter to pay tribute to de Lange.