Subaash passed away at SRM hospital, here.
"He was suffering from kidney failure and was on dialysis for the last few years. He passed away this morning," a source from the industry told IANS.
Subaash started his career as an assistant to Mani Ratnam in 1987 Tamil film "Nayagan", and a year later he made his directorial debut with Prabhu-starrer "Kaliyugam".
In 1990, he directed Vijayakanth-starrer Tamil actioner "Sathriyana, a blockbuster which earned him immense popularity.
He directed nearly 20 films with last one being 2005 Hindi actioner "Insan", which featured Ajay Devgan, Akshay Kumar , Esha Deol and Lara Dutta.
He had also assisted Rajkumar Santoshi on a few projects.
As a writer, he had worked on Hindi films such as "Sunday", "Entertainment" and "Housefull 3".
Remembering Subaash as a gentle and humble person, write Shridhar Raghavan wrote on his Twitter page:"Many took Subaash's stories and ideas without credit or money. He'd laugh "We are rivers sir. If a needy fellow comes with a bucket, let him."
Actress Radikaa Sarath Kumar wrote: "Very saddened to hear about the passing away of director K Subaash, a long time associate and director of 'Pavithra' film with Ajith and many more. Sad."
The last rites of Subaash will take place on Wednesday.