The outing at the Kennington Oval will go beyond experimenting with their highly skilled bowling attack, and quite a bit of focus will be on K L Rahul and Vijay Shankar, contenders for the number four slot.
While the arch lights will be firmly trained on their talismanic skipper, the number one batsman in 50-over as well as Test cricket, India, and their opponents would also keenly watch their fancied pace attack that is a mix of speed and guile.
In Rohit Sharma and Shikhar Dhawan as openers followed by Virat Kohli, India have one of the finest and potent top three in the world. Veteran Mahendra Singh Dhoni, all-rounder Kedar Jadhav and the big-hitting Hardik Pandya provide depth to the line-up.
In the bowling department, Jasprit Bumrah, the top-ranked ODI bowler in the world, leads the pace battery alongside Mohammed Shami, Bhuvneshwar Kumar and Hardik.
Wrist spinners Kuldeep Yadav and Yuzvendra Chahal add variety to India's attack, and Kohli sees them playing an influential role in the coming weeks.
Kohli has expressed confidence in his side's ability to live up to the billing, while his counterpart Kane Williamson also expressed how pleased he was to have the squad back together, with New Zealand having last played an ODI on February 19 against Bangladesh.
Squads:
India: Virat Kohli (capt), Jasprit Bumrah, Yuzvendra Chahal, Shikhar Dhawan, MS Dhoni (wk), Ravindra Jadeja, Kedar Jadhav, Dinesh Karthik (wk), Bhuvneshwar Kumar, Hardik Pandya, KL Rahul, Mohammed Shami, Vijay Shankar, Rohit Sharma, Kuldeep Yadav
New Zealand: Kane Williamson (capt), Tom Blundell (wk), Trent Boult, Colin de Grandhomme, Lockie Ferguson, Martin Guptill, Matt Henry, Tom Latham (wk), Colin Munro, Jimmy Neesham, Henry Nicholls, Mitchell Santner, Ish Sodhi, Tim Southee, Ross Taylor