Whole Genome Sequencing For Tuberculosis Bacteria Has Improved Diagnosis And Treatment Outcomes. Here's How

Whole genome sequencing is used for therapeutic innovations, including the newest generation of antitubercular drugs, to identify therapeutic targets, and track resistance mechanisms of tuberculosis.

The complete genomic sequence of Mycobacterium tuberculosis, the causative organism of tuberculosis, was first obtained in 1998, by Cole et al. The DNA sequence data for the entire Mycobacterium tuberculosis genome was obtained through whole genome sequencing. ( Image Source :Getty/Nature Journal )

The complete genomic sequence of Mycobacterium tuberculosis, the causative organism of tuberculosis, was first obtained in 1998, by Cole et al. The DNA sequence data for the entire Mycobacterium tuberculosis genome was obtained through whole genome sequencing. The whole genome has served as an extremely important resource to understand tuberculosis.  With the information obtained from the Mycobacterium tuberculosis genome, researchers have performed extensive research on tuberculosis and