"I am totally healthy and I am not suffering from any disease," he said in the statement in Hindi which was posted on his Twitter handle.
Home Minister Shah said he did not pay attention to these rumours but he thought it was important to clarify today because many BJP party workers were worried about his health.
The Home Minister taking a jibe at those spreading rumours wrote. "I request people to stop indulging in such talks and let me do my work, they should also go about their business," he added.
WATCH | Gujarat: Police arrests 4 for spreading fake news over Amit Shah's health
Amit Shah thanked well-wishers for inquiring about his health. The Home Minister signed off by saying he has no hatred towards those who spread the rumours.
This comes after Gujarat police have detained 4 persons in Ahmedabad, in connection with a fake tweet being circulated in the name of Shah.
National President of the BJP, JP Nadda, said making "inhuman" comments about the health of Home Minister Amit Shah is "extremely condemnable".
"Making inhuman comments about the health of Home Minister Amit Shah is extremely condemnable. Spreading such misleading remarks about anyone''s health shows the mindset of people doing so. I strongly condemn it and pray to God to grant them good sense," Nadda said in a tweet.