Guha did not elaborate on the circumstances which led him to take this decision.
On October 16, the varsity had announced that Guha will join it as 'Shrenik Lalbhai Chair' Professor of Humanities and director of the Gandhi Winter School.
Vice Chancellor Pankaj Chandra was not available for his comments upon Guha's announcement Thursday.
Ahmedabad University is a private, non-profit university that offers under-graduate, graduate and doctoral programmes in areas including engineering, business management, science and the humanities.
Guha has penned a number of books, the latest being "Gandhi: The Years That Changed the World, 1914-1948" which have received critical acclaim.