The 47-year-old actor took to Twitter to make the announcement and expressed his disappointment over not being able to work with one of his favourite directors.
"I am a huge crazy fan of Rohit Shetty and his films. As is my son. It breaks both our hearts that I'm not able to be a part of this film because of my injury. I'm well on my way to recovery but this is a huge opportunity and excitement lost," Madhavan tweeted.
In the end of last month, the '3 Idios' actor had shared a picture from the hospital bed after he underwent a shoulder surgery. He's apparently talking about the same injury that he's recuperating from post surgery.
"Cannot feel my right arm haha"- R Madhavan shares a pic from hospital bed post undergoing shoulder surgery
The movie, directed by Rohit and produced by Dharma Productions, features Ranveer Singh in the lead role of cop Sangram Bhalerao. Sara Ali Khan was recently roped in to play the female lead.
The director will start shooting for the hardcore action drama sometime around April. It is slated to release on December 28th, 2018.