The funds raised from the TIFF gala will help fund talent development programs at the Canadian festival to get more women behind and in front of the camera.
For its 42nd edition, the stylish event at Bell Lightbox will feature Chopra in conversation with festival artistic director Cameron Bailey.
Toronto will also be honouring the 'Mary Kom' star for her activism of devoting time to UNICEF as a goodwill ambassador and the Priyanka Chopra Foundation for Health and Education.
The 'Quantico' star recently made her Hollywood debut with 'Baywatch,' after bringing her Bollywood flicks like 'Mary Kom' in 2014 and 'What's Your Raashee?' in 2009 to the Toronto festival.
The main event is set to run from September 7.