The nuptials with Perello was performed at a British-owned fortress. The 33-year old Nadal met his wife through his younger sister Maribel, a childhood friend of Perello.
Nadal, the reigning US Open champion had to withdrew himself from Shanghai Masters following a wrist injury he sustained during Laver Cup.
It was the second year in a row that the 19-time Grand Slam champion failed to appear in Shanghai.
"As you all probably know, I had an inflammation on my left wrist during the Laver Cup and I haven't had the time to recover and practise to be ready for this amazing event," Nadal had said in a statement.
"I hope to be back in Shanghai for the 2020 tournament."
Tournament director Michael Luevano said, "We will obviously miss not having Rafa here at the Shanghai Masters. He has been an incredible supporter of the tournament and of tennis in China.
"Also, on a personal note, as well as speaking for the entire family at the Shanghai Masters, we wish Rafa and his fiance Maria Francisca all the very best for their upcoming wedding."