[Inputs BY: Dr Bani Kumar Mitra & Dr Konkon Mitra, Abha Surgy Centre]


In vitro fertilisation (IVF) has been a boon for many couples struggling with infertility. However, IVF treatment is not helpful in severe male infertility issues such as low sperm count, poor sperm motility & morphology or problems with sperm quality that make natural fertilisation difficult. 


In such cases, Intra-Cytoplasmic Sperm Injection (ICSI) offers a ray of hope. This advanced fertility treatment helps overcome male subfertility & is often used alongside In Vitro Fertilisation (IVF) to maximise the chances of conception.


If you are considering ICSI, here is an outline that you need to know about the procedure and how it could bring you one step closer to your dream of parenthood.


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What Is ICSI?


ICSI is a highly specialised fertility treatment where a single sperm is injected directly into an egg. This procedure is typically recommended when there are severe male infertility issues such as low sperm count, poor sperm motility, or problems with sperm quality that make natural fertilisation difficult. ICSI can also be used in cases of male infertility where previous IVF attempts have not been successful. (u can provide a picture here)


The ICSI Process: Step-by-Step



  • Ovarian Stimulation: Like IVF, ICSI begins with stimulating the ovaries to produce multiple eggs.

  • Egg Retrieval:  Once the eggs are mature, they are carefully retrieved through a minor surgical procedure. 

  • Sperm Collection: A sperm sample is collected from the male partner (or a sperm donor if needed). In cases of low sperm count or motility, sperm can be directly extracted from the testicles through a small procedure.

  • Sperm Injection: The magic of ICSI happens here. Under a microscope, a single healthy sperm is selected and injected directly into an egg. This bypasses many of the issues associated with sperm penetration, offering better chances of successful fertilisation.

  • Embryo Culture and Transfer: After fertilisation, the embryos are cultured for 3-6 days in the lab to ensure healthy development. Once ready, the best quality embryo is selected for transfer into the uterus, where it has the potential to implant and grow into a fetus.


ICSI Success Rates And Considerations


ICSI has revolutionised the treatment of male infertility and success rates are generally high. However, success depends on various factors, most important being age of the woman, quality of the eggs & sperm and the health of the woman undergoing treatment. Age, medical history and lifestyle factors of the couple play a vital role in determining the outcome of ICSI. It is important to remember that while ICSI offers great promise, it may not guarantee pregnancy. Multiple cycles might be necessary in some cases.


The Future Of ICSI


ICSI has evolved over the years, with ongoing advancements improving its success rates and reducing risks. New techniques and better understanding of sperm quality have made this procedure more effective, bringing hope to lakhs of couples struggling to conceive. ICSI is a groundbreaking fertility treatment that has helped many couples achieve their dreams of becoming parents. Whether you are dealing with male infertility or have faced challenges with IVF, ICSI could be the solution you have been waiting for. If you are considering ICSI, speak with a fertility specialist to understand your options and begin your journey towards parenthood with confidence.


[Disclaimer: The information provided in the article, including treatment suggestions shared by doctors, is intended for general informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.]