Dengue Recovery Tips: Papaya Leaf Juice For Boosting Platelets During Dengue Dengue fever is caused by the dengue virus, transmitted by female Aedes mosquitoes. The dengue virus lowers the platelet count by suppressing bone marrow through activated immune cells interleukins. Papaya leaf extract has shown a significant role in increasing platelet count in dengue patients. The extract contains compounds like flavonoids, alkaloids, anthraquinones, saponins, cardiac glycosides, and tannins. The extract contains compounds like flavonoids, alkaloids, anthraquinones, saponins, cardiac glycosides, and tannins. Papaya leaf extract can neutralise plasma with the dengue virus and significantly reduce platelet aggregation. Quercetin in papaya leaves inhibits dengue virus replication by targeting viral proteases NS2B and NS3. Papaya leaf extract also helps increase the WBC count. Papaya leaf extract supports vascular permeability reduction by mitigating proinflammatory factors and complement activation.